Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance
نویسندگان
چکیده
منابع مشابه
Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance.
Inflammation is well established to significantly impact metabolic diseases. The inflammatory protease caspase-1 has been implicated in metabolic dysfunction; however, a potential role for the related inflammatory caspases is currently unknown. In this study, we investigated a role for caspase-11 and caspase-12 in obesity and insulin resistance. Loss of caspase-12 in two independently generated...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2015
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.1501529